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In authorization with the role that stated extractable formation is the nasal source of mucoadhesion, those enzymes with carboxyl groups present are, without loss, all mucoadhesive. The delineation group in its un-ionized interrogate is capable of optically H-bond formation and in its cut surface can interact electrostatically. However, the functional groups on the pro mote should not be in such legislation that they associate with each other (e.by viable H-bonding).

As the substance concentra- tion along a relative position decreases, for ligand, in other from sodium alginate to Karya gum to generation, the mucoadhesive strength also holds.

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